Safer-by-Design Nanoparticles


Nanoparticles raise exciting possibilities to build new materials, to design targeted therapies or to store information. However, many questions remains regarding their impact on human health (toxicity) and on the environment (eco-toxicity). A strategy has recently emerged to mitigate their effect: it consists in involving toxicity studies from the design step.

Thanks to a collaboration with a team of biologists and physician at INSERM (Dr. Sophie Lanone team, Institut Mondor), we are developing "safer-by-design" nanoparticles. These nanoparticles are those that we are studying in other projects (metal phosphide, metal oxysulfides...). Contrary to carbon nanotube or nano-titania, these are still emerging nanoparticles, meaning that they did not yet find their way to large-scale application.

[Special Issue] Sustainable Design for Safer Nanotechnology

Opened for submission, this special issue of Nanomaterials (MDPI), guest-edited by Pr. Corinne Chanéac, Dr. Mélanie Auffan, Dr. Jérôme Rose and myself. Keywords: nanotoxicology | safer by design | eco-design | product lifecycle| environmental applications & implications.



µ-XRF of cells incubated with nanoparticles of gadolinium oxysulfide. Collected at ID21 in ESRF in November 2017.


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Sorbonne Université - LCMCP
Tour 34-44, bureau 412, CC174
4 Place Jussieu
75252 Paris Cedex 05, FRANCE
sophie.carenco* (* is @)
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